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Research Group Theoretical Stem Cell Biology

Parent Units:
Technische Universität Dresden (TUD)
German name: "Arbeitsgruppe Theoretische Stammzellbiologie".

Contact

web: https://tu-dresden.de/med/mf/imb/forschung/arbeitsgruppen-am-imb/ag-glauche-theoretische-stammzellbiologie
email: e-mail
phone: +49 (0)351 458-6051
fax: +49 (0)351 458-7222
postal address: Technische Universität Dresden (TUD), Research Group Theoretical Stem Cell Biology, Fetscherstraße 74, 01307 Dresden, Germany
office address: Technische Universität Dresden (TUD), Research Group Theoretical Stem Cell Biology, Blasewitzer Strasse 86, 01307 Dresden, Germany
partner: Technische Universität Dresden

Expertise

Theoretical Stem Cell Biology:

  • Hematopoietic stem cell aging (BMBF-funded project MessAge: Medical Systems Biology of Aging Hematopoiesis):
    • Clonal competition and clonal dominance
    • Age-related changes in the polarity of HSC divisions
  • Theoretical concepts of stem cell organization:
    • Proliferation- and differentiation control of haematopoietic stem cells
    • Clonal competition phenomena
    • Stem cell / niche interaction
    • Cell fate regulation of mouse embryonic stem cells
  • Disease and treatment models:
    • Chronic and acute myeloid leukaemia
    • Conceptual understanding of inherited bone marrow failure syndromes
    • Gene therapeutic approaches


Biostatistics / Bioinformatics:

  • Statistical analysis of dynamic processes and structures (analysis of cellular genealogies)
  • Image analysis, single cell tracking and genealogy reconstruction

Affiliations

Parent Units

name type actions
Institute for Medical Informatics and Biometry (IMB) Institute view

Last Update

Last updated at: 2016-10-20 10:16