Application: Recording of extracellular potentials from electrically active tissue samples.

Common read outs of interest:

• Neuronal action potentials (spontaneous or evoked)
• Field excitatory postsynaptic potentials (fEPSP)
• Local field potentials (LFP)

Technical specifications:

• Gain 1100, signal range: a few tens of µV (detectability depending on background activity) up to +/-3.7 mV
• 59 recording channels, various electrode sizes and layout configurations available
• Capacity for electric stimulation at any individual or any combination of electrodes
• Capacity for optic stimulation (wavelengths (in nm): 470, 513, 580, 640; combinable with the below mentioned filters; intensity scaleable; temporally patterned stimulation possible)
• Capacity to image the sample from below (objectives: 2x, 4x, 10x, 20x, additional 1.5x magnification) 
• Fluorescence imaging capacity (filters: CFP, GFP, TxRed, Cy5)

Cobinable with:

• Heat control (internal heating plate (cultures) and inline heater (acute tissue))
• Superfusion and drainage of fresh solutions
• Bathapplication of modulators
• Mechanic stimulation

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