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Research Group Medical System Biology and Biometry

Parent Units:
Technische Universität Dresden (TUD)
German name: "Arbeitsgruppe Medizinische Systembiologie und Biometrie".

Contact

web: https://tu-dresden.de/med/mf/imb/forschung/arbeitsgruppen-am-imb/ag-roeder-medizinische-systembiologie-und-biometrie
email: e-mail
phone: +49 (0)351 458-6060
fax: +49 (0)351 458-7222
postal address: Technische Universität Dresden (TUD), Research Group Medical System Biology and Biometry, Fetscherstraße 74, 01307 Dresden, Germany
office address: Technische Universität Dresden (TUD), Research Group Medical System Biology and Biometry, Blasewitzer Strasse 86, 01307 Dresden, Germany
partner: Technische Universität Dresden

Expertise

Theoretical Biology / Medical System Biology:

  • Theoretical concepts of stem cell organization (theoretical stem cell biology):
    • Proliferation- and differentiation control of haematopoietic stem cells
    • Cell fate regulation of mouse embryonic stem cells
    • Clonal competition phenomena
    • Stem cell / niche interaction
  • Mathematical models and computer simulation of stem cell development:
    • Single cell(agent)-based models of the stem cell organization
    • Dynamics of molecular regulation networks
  • Disease and treatment models / model-based design of clinical trials:
    • Chronic myeloid leukaemia
    • Gene therapeutic approaches


Biostatistics / Bioinformatics:

  • Statistical analyse of dynamic processes and structures:
    • Analysis of cellular genealogies (lineage trees)
    • Application of „mixed-effect“ models
  • Image analysis / image processing:
    • Single cell tracking and genealogy reconstruction
    • Model-based segmentation methods
  • Integratived methods for the analyse of molecular data:
    • (MicroArray-based) gene expression analysis
    • Next-generation sequencing

Affiliations

Parent Units

name type actions
Institute for Medical Informatics and Biometry (IMB) Institute view

Last Update

Last updated at: 2016-10-20 10:16