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Genetic Engineering of Stem Cells (Group)

Parent Units:
Technische Universität Dresden (TUD)
German name: "Engineering von Stammzellen".

Contact

web: http://www.biotec.tu-dresden.de/research/anastassiadis/
email:
phone: +49 (0)351 463-40127
address: Technische Universität Dresden (TUD), Genetic Engineering of Stem Cells, Tatzberg 47/49, 01307 Dresden, Germany
partner: Technische Universität Dresden

Expertise

The research interest in my lab is to unravel the molecular pathways that regulate self-renewal and lineage commitment of stem cells and the molecular mechanisms that are involved in cellular reprogramming. We work with mouse and human embryonic stem cells (mES, hES), neural stem cells (NSCs), mesenchymal stromal cells (MSCs) and induced pluripotent stem cells (iPS). My lab is also focusing on the development of genetic engineering tools that can be used to address the above questions.

 

Future Prospects

  • Correction of patient specific induced pluripotent stem cells by gene targeting
  • Dissect the role of histone demethylases in cellular reprogramming
  • Conditional immortalization for analyzing the lineage commitment of conditioanlly immortalized mesenchymal stromal cells

Affiliations

Parent Units

name
type
actions
Biotechnology Center of the TU Dresden (Biotec) Center view
CRTD - Center for Regenerative Therapies TU Dresden (CRTD) Center view

Last Update

Last updated at: 2016-01-29 15:35