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Structural Bioinformatics & Computational Biology (Group)

Parent Units:
Technische Universität Dresden (TUD)
German name: "Strukturelle Bioinformatik".

Contact

web: http://www.biotec.tu-dresden.de/research/pisabarro.html
email:
phone: +49 (0)351 463 40077
postal address: Technische Universität Dresden (TUD), Structural Bioinformatics & Computational Biology, 01062 Dresden, Germany
office address: Technische Universität Dresden (TUD), Structural Bioinformatics & Computational Biology, Tatzberg 47-51, 01307 Dresden, Germany
partner: Technische Universität Dresden

Expertise

Rational engineering and structure-based design for medical and biotechnological applications

Our group develops and applies computational strategies for functional genome annotation and rational engineering for target/drug discovery and biotechnology innovation.
By applying structure-based computational methods, molecular modeling and computer simulation techniques, and in very close collaboration with experimentalists, we try to decipher the relationships between biomolecular structure and function in order to understand the molecular basis of protein/DNA/other recognition, which will allow us to rationally intervene their biological function. Our current research focuses on the discovery and functional characterization of novel proteins, the rational engineering of proteins with improved functional properties, and de novo design of molecular scaffolds for a variety of biotechnological and biomedical applications.

Affiliations

Parent Units

name
type
actions
Biotechnology Center of the TU Dresden (Biotec) Center view

Last Update

Last updated at: 2019-07-03 10:07 CEST