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Institute for Pharmacology and Toxicology

Parent Units:
Technische Universität Dresden (TUD)
German name: "Institut für Pharmakologie und Toxikologie".

Contact

web: https://tu-dresden.de/med/mf/pt
email: e-mail
phone: +49 (0)351 458-6300
fax: +49 (0)351 458-6315
postal address: Technische Universität Dresden (TUD), Institute for Pharmacology and Toxicology, Fetscherstr. 74, 01307 Dresden, Germany
office address: Technische Universität Dresden (TUD), Institute for Pharmacology and Toxicology, Fiedlerst. 42 (2nd floor, Room C.20.050), 01307 Dresden, Germany
partner: Technische Universität Dresden

Expertise

The goal of our research is to understand biology of disease and to learn how to molecularly restore function to defective organs.  Our primary focus is  to clarify the pathophysiological mechanisms leading to cardiovascular diseases by using different in vitro and in vivo models. 

Because of the diversity in the genetic tools, the mouse model is one of the most important at our institute. We are researching the importance of specific signal proteins in the development of cardiac diseases using transgenic and knock-out mouse models. We are also using mouse models to identify molecules as pharmaceutical targets of cardiovascular diseases.

We are using the zebrafish as a model to understand why the fish can regenerate its heart and compare it with mammalian models of heart injury to improve the regeneration potential of patients.

In addition,  our institute is using the potential of induced pluripotent stem cells (iPS cells) to research human diseases and to develop individualised medical treatments.

Thus, our goal are to acquire a better understanding of cardiovascular pathophysiologies as well as to develop better clinical therapies and diagnostic tools for cardiovascular diseases.

 

 

Affiliations

Parent Units

name type actions
Faculty of Medicine Carl Gustav Carus Faculty view
Medical Theoretical Center (MTZ) Center view

Last Update

Last updated at: 2016-06-09 09:44 CEST